Diazepam

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Among all the existing drugs for neurological diseases, Valium occupies a prominent position. This is an anxiolytic, produced in the form of tablets, solution for intramuscular and intravenous administration.
Valium is intended to eliminate neurotic and neurosis-like conditions accompanied by increased anxiety. It is used to eliminate psychomotor agitation in patients with epileptic seizures or convulsive syndrome of various etiologies. In addition, Valium helps relieve increased muscle tone in patients suffering from acute cerebrovascular accidents or who have been infected with tetanus. It is used to relieve withdrawal symptoms in patients with chronic alcoholism.
Valium, in combination with analgesics or other neurotropic drugs, is used for ataralgesia and premedication during various diagnostic procedures in obstetric and surgical practice. It is also used as part of the complex treatment of hypertension, attacks of which are accompanied by increased anxiety, increased excitability, frequent hypertensive crises, vasospasm, and climatic and menstrual disorders.


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Action of Valium

Valium acts at a reflex level. It depresses the central nervous system, leading to the inhibition of nerve impulses and subcortical structures of the brain. Most of the drug's action is focused on synaptic transmission in the hypothalamus, limbic system, and thalamus.



The drug has a sedative effect, relieves seizures, and can act as a sleeping pill. This is primarily a tranquilizer aimed at suppressing brain impulses in presynaptic transmission and after it.



Contraindications

Valium is not used to treat patients with hypersensitivity to benzodiazepine derivatives, severe forms of myasthenia gravis, closed-angle glaucoma, drug or alcohol addiction, sleep apnea syndrome, or acute drug intoxication.



The drug is prescribed with caution to patients with a history of renal or liver failure, a tendency to take psychotropic substances and organic brain damage.



Particular attention is paid to Valium in the treatment of alcohol dependence. It helps to get rid of withdrawal symptoms, reduce the excitability of the central nervous system, and tune in to the planned treatment of alcoholism using coding or therapy.
It is worth noting that drinking alcohol during treatment with Valium should be completely avoided, including MEDICINES ONLINE containing alcohol. When interacting with alcohol, the drug only enhances its effect on the central nervous system. Brain neurons are inhibited.


Use during pregnancy and breastfeeding

Valium is not used to treat women during pregnancy in the first and third trimesters. If it is necessary to prescribe the drug during lactation, then the question of stopping breastfeeding is raised.


Directions for use and doses

To relieve psychomotor agitation, accompanied by increased anxiety, the patient is administered 10 to 20 mg of the drug; if necessary, the administration of Valium can be repeated every 3 or 4 hours. When treating tetanus, the drug is administered intramuscularly or intravenously from 10 to 20 mg, with an interval of 2 to 8 hours.


Overdose

With an overdose of Valium, patients may experience depression of consciousness, decreased reflexes up to complete areflexia, decreased pain threshold, ataxia, dysarthria, blurred vision, hypotension, depression of the heart and lungs.
To improve the patient's condition, he is given forced diuresis, gastric lavage, symptomatic therapy and the administration of flumazenil.



Side effects

Uncontrolled use of the drug can cause a number of side effects. The central nervous system is especially susceptible to this. From its side, it is noted:


  • disorientation,
  • dizziness,
  • headache,
  • drowsiness,
  • decreased reflexes,
  • tremor,
  • drowsiness.

From the gastrointestinal tract:

  • heartburn,
  • constipation,
  • lack of appetite,
  • high salivation,
  • nausea and vomiting,
  • pain in the abdomen.


From the heart and blood vessels, fluctuations in blood pressure, thrombosis, arrhythmia, tachycardia, and anemia are possible.



The genitourinary system also suffers. In case of an overdose, uncontrolled urination, decreased libido, and cycle disruption in women are possible.



If Valium and its components are not suitable for the patient, this may be indicated by skin rashes and itching.



Interactions with other drugs should also be monitored by the attending physician. In general, it is worth avoiding the simultaneous use of drugs that affect the central nervous system and drugs containing alcohol.