Although a balanced, low-calorie diet and consistent exercise form the cornerstone of weight loss, certain medications can provide significant support. Phentermine stands out as one such medication, widely recognized as one of the most commonly prescribed weight loss ONLINE MEDICINES globally. Research indicates its efficacy in facilitating short-term weight loss when combined with a controlled diet and regular exercise. Nonetheless, employing phentermine for weight loss entails potential risks and side effects.

Twenty. Provisions worth knowing

Phentermine, a prescription medication for weight loss, gained FDA approval in 1959 for short-term usage of up to 12 weeks in individuals aged 16 and above. Classified as a controlled substance due to its chemical resemblance to the stimulant amphetamine, it's accessible solely through a prescription. Your physician might recommend phentermine if you're obese, defined as having a body mass index (BMI) of 30 or higher. It could also be prescribed if your BMI exceeds 27 and you have accompanying health issues like hypertension, high cholesterol, or type 2 diabetes.

Belonging to the class of drugs known as anorectics or appetite suppressants, phentermine functions by curbing your appetite, thereby reducing calorie intake and facilitating weight loss. Though the precise mechanisms behind phentermine's appetite-reducing effects remain elusive, it's believed to elevate neurotransmitter levels in the brain. These neurotransmitters—norepinephrine, serotonin, and dopamine—act as chemical messengers, regulating hunger. Consequently, heightened levels of these neurotransmitters diminish your appetite.

However, tolerance to phentermine's appetite-suppressing properties may develop within a few weeks. If this occurs, it's advisable not to escalate the dosage but rather discontinue its use altogether.

Administration Protocol

Each individual's treatment plan, including dosage, is tailored based on their specific condition and response to therapy. Typically, the course of Phentermine treatment spans three months. It's recommended to take Phentermine 10-14 hours before bedtime to avoid interference with sleep patterns.

The standard daily dose is 30 mg, but your physician may modify it as needed. Phentermine should not be taken more than once daily, nor should the tablets be broken or chewed before ingestion.

There is no need to assume that Phentermine is a magic drug that will help you quickly lose weight. A prerequisite is a change in lifestyle: proper balanced nutrition, and physical activity. This drug is only a supplement, and its effectiveness can only be assessed after a few weeks (from 4 weeks).

Adverse Effects and Precautions

Phentermine is designated for short-term usage due to the absence of long-term safety studies. However, the FDA has sanctioned its extended use when combined with topiramate, as the dosage of these compounds is below the maximum doses of the individual drugs. While severe side effects are uncommon, studies have identified several potential side effects associated with the combination of phentermine and topiramate.

Commonly Reported Side Effects:

• Dry mouth
  
• Insomnia
  
• Dizziness
  
• Increased heart rate
  
• Flushing of the skin
  
• Fatigue
  
• Restlessness
  
• Irritability
  

Additionally, phentermine should not be prescribed alongside monoamine oxidase inhibitors (MAOIs), a class of antidepressant medications.

Contraindications

Phentermine hydrochloride 37.5 mg is not advised for individuals who:

• Have diabetes
• Have an overactive thyroid gland
• Have experienced allergic reactions to this medication
• Suffer from glaucoma
• Have liver or kidney issues

Twenty. When the risks outweigh the benefits

Alcohol consumption is discouraged while taking phentermine due to potential adverse reactions. Furthermore, this medication is not recommended for children under 16 years of age or elderly individuals.